Faculty at School of Natural Sciences
Vascular Biology | Lymphatic System | Developmental Biology | Regeneration | Genomics
Vascular networks, the lymphatic vessels (LV) and the blood vessels (BV), in the vertebrate body display an extraordinary range of morphological and functional diversity. These complex LV/BV systems, composed of endothelial cells (ECs), engage in close interactions with diverse organ microenvironments. Our focus lies in unraveling how ECs develop distinct vessel and organ-specific identities and understanding their vital roles in organ development, function and regeneration.
Postdoctoral Research : 2016-2023; Weizmann Institute of Science (Prof. Karina Yaniv’s Group)
- 2019-21 : Senior Postdoctoral Fellowship (Weizmann Institute of Science)
- 2018-19 : Dean of Faculty Postdoctoral Fellowship (Weizmann Institute of Science)
- 2016-18 : EMBO Long-term Fellowship (European Molecular Biology Organization)
- 2008 : PhD Scholarship (TIFR graduate programme in Biology)
- 2008 : CSIR Junior Research Fellowship (CSIR-UGC NET)
Generation of specialized blood vessels via lymphatic transdifferentiation
Das RN*, Tevet Y, Safriel S, Han Y, et al. (2022) Generation of specialized blood vessels via lymphatic transdifferentiation. Nature 606, 570-575 (2022)
* - Co-corresponding author
Sensory Neuron-Derived Eph Regulates Glomerular Arbors and Modulatory Function of a Central Serotonergic Neuron
Singh AP*, Das RN*, Rao G*, Aggarwal A, Diegelmann S, et al. (2013) Sensory Neuron-Derived Eph Regulates Glomerular Arbors and Modulatory Function of a Central Serotonergic Neuron. PLoS Genet 9(4): e1003452.
* - Equal Contribution
A Tendon Cell Specific RNAi Screen Reveals Novel Candidates Essential for Muscle Tendon Interaction Tiwari P, Kumar A*, Das RN*, Malhotra V, VijayRaghavan K (2015) A Tendon Cell Specific RNAi Screen Reveals Novel Candidates Essential for Muscle Tendon Interaction. PLoS ONE 10(10): e0140976.
* - Equal Contribution
Discovering New Progenitor Cell Populations through Lineage Tracing and In Vivo Imaging
Das RN*, Yaniv K* (2020) Discovering New Progenitor Cell Populations through Lineage Tracing and In Vivo Imaging. Cold Spring Harb Perspect Biol. 2020 Oct 1;12(10): a035618.
* - Co-corresponding author
Lymphatic-to-blood vessel transdifferentiation in zebrafish (News & Views, Nature Cardiovascular Research, 2022)
https://www.nature.com/articles/s44161-022-00073-1
Blood vessels originating from lymphatic vessels are found to be tailored to specific functions (Phys.org, 2022)
https://phys.org/news/2022-05-blood-vessels-lymphatic-tailored-specific.html
Scientists Discover That Blood Vessels Remember Their Origins (Scitechdaily.com, 2022)
https://scitechdaily.com/scientists-discover-that-blood-vessels-remember-their-origins/
2023 – Oral presentation in the New Frontiers in Cardiac and Vascular Biology symposium, Rehovot, Israel.
2023 – Oral presentation (online) in the European Vascular Biology Organization seminar series as a part of Young Investigator Spotlight.
2021 – Oral presentation in the 6th Israeli Zebrafish meeting, held in Jerusalem, Israel.
2021 – Oral presentation (online) in the Virtual Southwest Society for Developmental Biology Meeting.
2019 – Oral presentation in the EMBO Fellows’ Meeting, held in Heidelberg, German
- 2021 – ePoster presentation (online) in the Lymphatic Forum.
- 2018 – Poster presentation in the 20th International Vascular Biology Meeting 2018 (IVBM2018), held in Helsinki, Finland.
- 2018 – Poster presentation in the IISER-WIS conference on chemical biology, held in Indian Institute of Science Education and Research, Pune, India.
- 2017 – Poster presentation in the 10th European zebrafish meeting, held in Budapest, Hungary.
- 2014 – Poster presentation in the 6th Maggot Meeting: "Behavioral Neurogenetics of larval Drosophila: Molecules, Circuits, Computation& Robotics" held in Atami, Japan.
Provided manuscript reviews for the journals - Life Science Alliance and Cell Biology International (Wiley).