SCHOOL OF NATURAL SCIENCES
NATURAL SCIENCES
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Faculty
Department of Chemistry
Gouriprasanna Roy
Assistant Professor,
Department of Chemistry,
School of Natural Sciences
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Education Details
Ph.D in Chemistry (With ), Department of Inorganic & Physical Chemistry, Indian Institute of Science (IISc), Bangalore, India, Aug 2002 - May 2007.
M.Sc. in Chemistry, University of Calcutta.
B.Sc. in Chemistry, University of Calcutta.
Professional Experience
  • Assistant Professor, Department of Chemistry, School of Natural Science, Shiv Nadar University, November 2012

  • Skaggs Postdoctoral Fellow (with ), Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, San Diego, CA, USA. Dec 2011 - Sept 2012.

  • OHSU Postdoctoral fellow (with ), Department of Physiology and Pharmacology, Oregon Health and Science University, Portland, Oregon, USA, Jan 2008 - Nov 2011.

  • IISc Research Associate (With ), Department of Inorganic & Physical Chemistry, Indian Institute of Science (IISc) Bangalore, May 2007 - Dec 2007.
Research Interests
Medicinal Chemistry and Drug Discovery; Bioorganic and Bioinorganic Chemistry; Drug Delivery; Nanomedicine; Chemical Biology.

Research in our laboratory is focused on two major areas: chemistry (Organic / Inorganic / nanomaterial) and biology, at the interface of chemistry and biology. Research group aims to understand the roles of proteins that play in physiological and pathological process and to use this knowledge to identify novel therapeutic targets for the treatment of complex diseases. Goal is to develop the engineering solutions for those complex diseases and to achieve our goals we develop and apply new technologies that bridge the fields of chemistry and biology. A large variety of powerful tools are used to explore the chemistry–biology interface—a unique and exciting opportunity for students to engage in a number of existing multi-disciplinary research. Students will be exposed to a broad range of techniques in chemistry as well as biology research focused on organic, inorganic, nanomaterial and polymer synthesis, characterization tools, protein purification, gel electrophoresis, cell biology etc.
Significant Publications
  • Gouriprasanna Roy (Principal Investigator), Mainak Banerjee (PhD Student), Ramesh Karri (PhD Student), Ashish Chalana (PhD Student) and Ranajit Das (PhD Student). DERIVATIVES OF IMIDAZOLE AND BENZIMIDAZOLE, METHOD OF PREPARATION AND USE THEREOF. Filed Provisional Patent Application (Patent App. No. 201611011508).

  • Banerjee, M.; Karri, R.; Roy, G. Detoxification of Mercury: Bioremediation to Chemical Degradation, in “Metal-Microbe interactions and bioremediation: Principle and applications for toxic metals” published by Taylor & Francis (CRC Press), Ed: Das, S. and Dash, H. R.; 2016, in press.

  • Banerjee, M.; Karri, R.; Rawat, K. S.; Muthuvel, K.; Pathak, B.; Roy, G.* “Chemical Detoxification of Organomercurials”
    Angew. Chem., 2015, 127, 9455 - 9459.
    Angew. Chem. Int. Ed., 2015, 54, 9323 - 9327.

    Impact factor: 11.3

    This article is highlighted in inside cover page in Angewandte Chemie

    Angew. Chem., 2015, 127, 9551.
    Angew. Chem. Int. Ed., 2015, 54, 9419.


    This article is also highlighted by press coverage in “The Economic Times”, “The Asian Age”, “India Education Diary”, “CareerLinks” and in “DNA” newspapers.

  • Manna, D.; Roy, G.; Mugesh, G.* “Antithyroid Drugs and their Analogues: Synthesis, Structure and Mechanism of Action.”
    Account of Chemical Research, 2013, 46, 2706 – 2715.
    Impact Factor: 22.323

  • Roy, G.*; Jayaram, P, N; Mugesh, G.* "Inhibition of Lactoperoxidase-catalyzed Oxidation by Imidazole-based Thiones and Selones: A Mechanistic Study".
    Chemistry - An Asian Journal, 2013, 8, 1910-1921.
    Impact Factor: 4.5; (* corresponding author)

  • Roy, G.; Placzek, E.; Scanlan, T. S. "ApoB-100-containing lipoproteins are major carriers of 3-iodothyronamine (T1AM) in circulation".
    Journal of Biological Chemistry, 2012, 287, 1790-1800.
    Impact Factor: 5.3.

  • Roy, G.; Bhabak, K; Mugesh, G. "Interactions of Antithyroid Drugs and their Analogues with Halogens and their Biological Implications",
    Crystal Growth & Design, 2011, 11, 2279–2286.
    Impact Factor: 4.891

  • Roy, G.; Bhabak, K; Mugesh, G. "Interactions of Antithyroid Drugs and their Analogues with Halogens and their Biological Implications",
    Crystal Growth & Design, 2011, 11, 2279–2286.
    Impact Factor: 4.891

  • Das, D.; Roy, G.; Mugesh, G. “Antithyroid Drug Carbimazole and Its Analogues: Synthesis and Inhibition of Peroxidase-Catalyzed Iodination of L-Tyrosine”.
    J. Med. Chem., 2008, 51, 7313 – 7317.
    Impact Factor: 5.447

  • Roy, G.; Nethaji, M.; Mugesh, G. "Interaction of Anti-Thyroid Drugs with Iodine: The Isolation of Two Unusual Ionic Compounds Derived from Se-Methimazole."
    Org. Biomol. Chem. 2006, 4, 2883–2887.
    Impact Factor: 3.562
    This paper has been featured on the Cover Page of the Journal.

  • Roy, G.; Mugesh, G. "Anti-Thyroid Drugs and Thyroid Hormone Synthesis: Effect of Methimazole Derivatives on Peroxidase-Catalyzed Reactions."
    J. Am. Chem. Soc. 2005, 127, 15207–15217.
    Impact Factor: 12.113

  • Roy, G.; Nethaji, M.; Mugesh, G. "Biomimetic Studies on Anti-thyroid Drugs and Thyroid Hormone Synthesis."
    J. Am. Chem. Soc. 2004, 126, 2712–2713.
    Impact Factor: 12.113
National & International Recognition
  • Received “Excellency Award” for outstanding commitment and dedication to the advancement of Shiv Nadar University during 2011-2014. Award was presented by Shiv Nadar University (SNU).

  • Awarded “Prof. S Soundararajan Medal” for “BEST THESIS” in the academic year 2007-2008. Award was presented by Indian Institute of Science (IISc), Bangalore, India.

  • Selected for Alexander von Humboldt Research Fellowship for postdoctoral research (with Prof. Michael Famulok), awarded by AvH Foundation (November 2008), Bonn, Germany.

  • Awarded Research Associate fellowship (May 2007–Jan 2008) by Indian Institute of Science (IISc), Bangalore, India.

  • One of the Best Poster Award in the "Third Symposium on Advances in Bioinorganic Chemistry (SABIC-2004)" in Conjunction with "Second Asian Biological Inorganic Chemistry Conference (AsBIC-II)" at Goa, India, Dec 2004.

  • Received the “Vasudevamurthy-Soundarajan Prize” for the “Best Performance in the Course Work” for the Academic Year 2002-03 in the Department of Inorganic and Physical Chemistry (IPC), Indian Institute of Science, Bangalore, India.

  • Junior/Senior Research Fellowships (Aug 2002–May 2007) awarded by CSIR, India.

  • Qualified national test “GATE-2001” and national test “CSIR-NET-2001”.

  • Shasanka Shekar Dey” memorial fellowship during class XII, awarded by Akui Union High School, Akui, Bankura, WB, India.
Selected Lectures/Conference
  • Delivered an invited lecture in the conference of the “International Symposium on Clusters, Cluster-Assemblies and Nanomaterials (ISCAN)” Thiruvananthapuram, Kerala, India March 9 - March 12, 2016”.

  • Delivered an invited lecture in the conference of the 6th International Conference on Metals in Genetics, Chemical Biology and Therapeutics (ICMG-2016), IISc, Bangalore, February 17-20, 2016.

  • Delivered an invited lecture in the conference of the “52nd Annual Convention of Chemists 2015 and International Conference on Recent Advances in Chemical Sciences”, organized by Indian Chemical Society, December 28–30 at JECRC University, Jaipur, Rajasthan.

  • Delivered an invited lecture in the symposium of “Modern Trend in Inorganic Chemistry (MTIC-XVI), December 3-5, 2015, Jadavpur University, Kolkata, India.

  • Roy, G. "Detoxification of Toxic Organomercurial Compounds: A Bioinorganic Chemistry Approaches". Delivered an invited Lecture in Indo-French Seminar on “Bio-inorganic Approaches to Current Health Problems”, March 24-28, 2014, Department of Chemistry, Pondicherry University, Pondicherry – 605 014, India.

  • Delivered an invited lecture on “Regenerative Medicine for Hematologic Malignancies” in Young Investigator Meeting, October 8-10, 2011, Boston (YIM-Boston 2011).

  • Roy, G.; Scanlan, T. Delivered a lecture on “Identification of 3-Iodothyronamine Binding Protein in Human Serum” NORM2011, 28th JUN2011, American Chemical Sociaty, Portland Section, Portland, Oregon, USA.
Executive Summary
Dr. Gouriprasanna Roy obtained his PhD from Indian Institute of Science, Bangalore in the area of Bioorganic / Bioinorganic chemistry. In 2008, he joined Oregon Health and Science University (OHSU) in the Department of Physiology and Pharmacology to work with Prof. Thomas S Scanlan. Following this he moved to work with Prof. Peter G Schultz, at The Scripps Research Institute (TSRI), where he focused on the development of drugs for the treatment of inflammatory bowel disease (IBD), different autoimmune diseases.
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